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Clinical decision rule

Kocher Criteria

Kocher Criteria for Septic Arthritis of the Hip

The Kocher criteria estimate the probability that a child with an irritable hip has septic arthritis rather than transient synovitis, using four independent predictors — non-weight-bearing, fever above 38.5 °C, ESR above 40 mm/hour and white cell count above 12,000 — with predicted probability rising from under 0.2% when none are present to over 99% when all four are.

No licence required4 items~1 min0–4, lower is better

Independent predictors

Assess a child presenting with an acutely irritable hip. All four predictors are needed to place the child on the probability gradient.

1Non-weight-bearing on the affected side

Unable or unwilling to bear weight on the affected hip.

2Temperature above 38.5 °C

History of fever or measured temperature above 38.5 °C (101.3 °F).

3ESR above 40 mm/hour

Erythrocyte sedimentation rate.

4Serum white cell count above 12,000 cells/mm³

Peripheral white blood cell count.

What the Kocher Criteria mean

Kocher Criteria scores run from 0 to 4, where a lower score is better. The bands below are conventional reporting categories, not diagnostic cut-offs.

  • Low probability0–1

    Transient synovitis is the more likely diagnosis.

  • Indeterminate2–2

    Neither diagnosis can be excluded on the criteria alone; investigate further.

  • High probability3–4

    Treat as septic arthritis until proven otherwise.

Published criteria and reliability

The published cut-offs that define this instrument, and the measured agreement between observers using it. Each is reported with the population it was derived in.

TypeValueSubscalePopulationFollow-upSource
Criterion0 predictors — 0.2% probability—Derivation cohort, Boston 1979–1996—Kocher MS 1999
Criterion1 predictor — 3.0% probability—Derivation cohort, Boston 1979–1996—Kocher MS 1999
Criterion2 predictors — 40.0% probability—Derivation cohort, Boston 1979–1996—Kocher MS 1999
Criterion3 predictors — 93.1% probability—Derivation cohort, Boston 1979–1996—Kocher MS 1999
Criterion4 predictors — 99.6% probability—Derivation cohort, Boston 1979–1996—Kocher MS 1999
CriterionPredicted probabilities were substantially lower at every predictor count on prospective validation—Prospective validation cohort, same institution—Kocher MS 2004

Criterion is a published cut-off, definition or performance figure belonging to a classification or decision rule — it is not a change score and should not be read as one.

How the score is calculated

Stated in full so the calculation can be independently checked, and reproduced by hand if needed.

Four independent predictors are assessed: non-weight-bearing on the affected side, a history or measurement of temperature above 38.5 °C, an erythrocyte sedimentation rate above 40 mm/hour, and a serum white cell count above 12,000 cells/mm³. The number of predictors present maps to a predicted probability of septic arthritis: none 0.2%, one 3.0%, two 40.0%, three 93.1% and four 99.6% in the original derivation cohort. The criteria are a probability gradient, not a diagnostic test, and do not replace joint aspiration where suspicion is high.

Instrument profile

Developer
Mininder S. Kocher and colleagues
Institution
Boston Children's Hospital, Harvard Medical School
First published
1999
Items
4
Response format
Four Yes/No predictors
Score range
0 to 4
Direction
Lower score = better
Completion time
About 1 minutes
Age range
Children, derived in a cohort with a median age of about 5 years
Regions
Hip, Paediatric
Conditions
Septic arthritis, Transient synovitis, Irritable hip, Paediatric limp
Validity
The predictors were independently significant on multiple logistic regression in the derivation cohort, and the rule remains the most widely taught approach to the irritable child’s hip.
Reliability
Performance degrades outside the derivation setting. Independent validations have consistently reported lower probabilities at each predictor count, so the rule is best used to stratify urgency rather than to give a patient a number.

When to use the Kocher Criteria

Well suited to

  • A child presenting with an acutely painful or irritable hip where septic arthritis and transient synovitis are the competing diagnoses.
  • Stratifying urgency and deciding whether to proceed to ultrasound and aspiration.

Limitations and poor fits

  • As a reason to withhold aspiration when clinical suspicion is high — a low predictor count does not exclude septic arthritis.
  • In neonates, immunocompromised children, or those already on antibiotics, where the inflammatory markers are unreliable.
  • For joints other than the hip, and for post-operative or penetrating-injury septic arthritis, which were not in the derivation cohort.

Kocher Criteria compared with other instruments

Instruments measuring a related construct, with the practical difference between them.

InstrumentItemsRangeWhat it adds
CCI170–37The Charlson Comorbidity Index is a weighted checklist of 16 comorbid conditions that produces a comorbidity score of 0 to 33, to which up to 4 points are added for age, and which estimates 10-year survival at roughly 98% for a total of 0, 90% for 2, 53% for 4 and 21% for 5.

Copyright and permitted use

Published openly because it is the question every clinician and researcher asks before using an instrument, and almost nobody answers it.

No licence required

The Kocher criteria are a published clinical prediction rule. The predictors and their probabilities are freely reproducible and no licence is required.

References

  1. Kocher MS, Zurakowski D, Kasser JR. Differentiating between septic arthritis and transient synovitis of the hip in children: an evidence-based clinical prediction algorithm. Journal of Bone and Joint Surgery (American). 1999.PMID 10608376
  2. Kocher MS, Mandiga R, Zurakowski D, Barnewolt C, Kasser JR. Validation of a clinical prediction rule for the differentiation between septic arthritis and transient synovitis of the hip in children. Journal of Bone and Joint Surgery (American). 2004.PMID 15173279
  3. Caird MS, Flynn JM, Leung YL, Millman JE, D’Italia JG, Dormans JP. Factors distinguishing septic arthritis from transient synovitis of the hip in children: a prospective study. Journal of Bone and Joint Surgery (American). 2006.PMID 16757758

Editorial status

This page has not yet been signed off by a named clinical reviewer. The scoring logic is stated in full above so it can be independently verified, and every threshold is traceable to its source. See our editorial methodology.